Southern Indiana Hotels

Do you want a hotel in the heart of our walkable downtowns? How about a place to stay near the Ohio River or near a business center?

We've got a variety of hotels to suit your needs. Search our hotel listings for a place to stay in Jeffersonville, Clarksville, New Albany, or any of the surrounding areas.

Hotels near I-65 and Louisville's East End 

Along the Interstate 65 corridor from Jeffersonville to Clarksville and east to Charlestown, you'll find an array of comfortable, budget-friendly options, most within 10 minutes of downtown Louisville. Many of these are part of national chains with local options as well.

Options along I-65 offer wonderful access to Louisville. The Sheraton Louisville Riverside Hotel, Radisson Hotel Louisville North, and Fairfield Inn and Suites are some of the national brand hotel options. They offer comfortable accommodations at wallet-friendly prices.

Hotel near downtown and West Louisville

Just off Interstate 64 line, you'll find national hotel brands in New Albany, Georgetown and other areas of Floyd County, like the Holiday Inn Express and Hampton Inn by Hilton New Albany Louisville West. These offer direct access to I-64 going to downtown Louisville or heading West towards St. Louis.

Wherever you stay in Southern Indiana, whether it is at one of the convenient national brand hotels or a local option, our accommodations offer excellent access to the interstates and Louisville, Kentucky.