Southern Indiana Hotels

Do you want a hotel in the heart of our walkable downtowns? How about a place to stay near the Ohio River or near a business center? 

We've got a variety of hotels to suit your needs. Search our hotel listings for a place to stay in Jeffersonville, Clarksville, New Albany, or any of the surrounding areas. Or search to find a bed and breakfast inn. SoIN has plenty of options from which to choose.

Hotels near I-65 and Louisville's East End

Along the Interstate 65 corridor from Jeffersonville to Clarksville and east to Charlestown, you'll find an array of comfortable, budget-friendly options, most within 10 minutes of downtown Louisville. Many of these are part of national chains with local options as well.

Options along I-65 offer wonderful access to Louisville. The Sheraton Louisville Riverside Hotel, Radisson Hotel Louisville North, and Fairfield Inn and Suites are some of the national brand hotel options. They offer comfortable accommodations at wallet-friendly prices.

Hotel near downtown and West Louisville 

Just off Interstate 64 line you'll find national hotel brands in New Albany, Georgetown and other areas of Floyd County like the Holiday Inn Express and Best Western Plus. These offer direct access to I-64 going to downtown Louisville or heading West towards St. Louis. 

Wherever you stay in Southern Indiana whether it is at one of the convenient national brand hotels or a local option, our cozy accommodations offer excellent access to the interstates and Louisville, Kentucky.